Protein name:
Suppressor of cytokine signaling 2 (SOCS-2) ;
Alternative:
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Interacts with IGF1 receptor, prolactin receptor and growth hormone (GH) receptor. Associates with the Elongin BC complex.
Function:
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway (By similarity). Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Location:
N/A
Protein Attributes:
50:
MTLRCLEPSG | NGAEGTQSQW | GTSGSAEEPS | PEAARLAKAL | RELSHTGWYW |
100:
GSMTVNEAKE | KLKEAPEGTF | LIRDSSHSDY | LLTISVKTSA | GPTNLRIEYQ |
150:
DGKFRLDSII | CVKSKLKQFD | SVVHLIDYYV | QMCKDKRTGP | EAPRNGTVHL |
198:
YLTKPLYTSA | PPLQHLCRLT | INKCTGTIWG | LPLPTRLKDY | LEEYKFQV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
Pig
Polyclonal Antibody for Pig SOCS-2
Polyclonal Antibody for Pig SOCS-2
Polyclonal Antibody for Pig SOCS-2
Polyclonal Antibody for Pig SOCS-2
Polyclonal Antibody for Pig SOCS-2
Monoclonal Antibody for Pig SOCS-2
Monoclonal Antibody for Pig SOCS-2
Monoclonal Antibody for Pig SOCS-2
Monoclonal Antibody for Pig SOCS-2
Monoclonal Antibody for Pig SOCS-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.
"Cloning of the pig SOCS2 gene."
Chao S.
,
Wen D.B.
,
She Y.G.
Submitted (2006-11) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Bamei .